A client has moderate-to-severe hypotonic extracellular fluid loss. Which IV fluids can be administered to correct the fluid balance?

10% dextrose in water
5% dextrose and 0.45% normal saline
5% dextrose in 0.9% saline


• Hypotonic dehydration refers to depletion of fluids and electrolytes with greater losses of electrolytes, resulting in hypotonic extracellular fluid

• 10% dextrose in water, 5% dextrose in 0.9% saline, and 5% dextrose in 0.45% saline are all considered hypertonic solutions, raising the osmolality of ECF

• Lactated Ringer's, 0.9% normal saline, and 5% dextrose in 0.225% saline are all isotonic solutions, capable only of expanding the ECF

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