A client has orders for a once-daily nitroglycerin transdermal patch. To properly administer the medication, the nurse should do which of the following?


• Application sites for nitroglycerin transdermal patches must be rotated every application to prevent skin irritation and sensitization. 

• The preferred site for a nitroglycerin patch is the chest. It must be dry, clean, and hairless. Avoid placing the patch on irritated sites or areas with cuts.

• Nitroglycerin patches must be applied for 12–14 hours followed by a 10–12 hour nitrate-free period to avoid developing tolerance. 

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