A newly diagnosed diabetic is receiving consultation about the disease process. The nurse explains that insulin is normally secreted from the


• Insulin is synthesized and released from the beta cells of the islets of Langerhans, which is the endocrine section of the pancreas.

• The endocrine portion accounts for only 2% of the pancreas.

• Insulin release is primarily stimulated by glucose, but it is also stimulated by amino acids, acetylcholine, and certain drugs.

• Insulin is released from the beta cells in two phases. It is released rapidly in response to increased glucose levels and slowly to maintain a consistent glucose level throughout the body.

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