A nurse is assessing multiple skin lesions on a patient with pemphigus vulgaris. The skin is easily rubbed off when the nurse applies slight friction. This best describes which of the following?

Explanation

• Nikolsky's sign is positive when slight friction or rubbing causes exfoliation of the skin

• A positive Nikolsky's sign is a hallmark of pemphigus vulgaris, a chronic autoimmune disease that causes painful blisters

• Blumberg's sign is the presence of rebound tenderness in the abdomen and is indicative of peritonitis

• Murphy's sign is indicative of cholecystitis

• O'Connor's sign does not exist

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