• Ethosuximide (Zarontin) is used to treat petit mal seizures or absence seizures and most commonly causes GI distress such as nausea, vomiting, abdominal pain, and diarrhea.
• Additional adverse effects may include ataxia, irritability, hyperactivity, headaches, rash, and gingival hyperplasia.
• Ethosuximide is not recommended during pregnancy (Catagory D) or for mothers who are breastfeeding.
• Ethosuximide works by depressing the motor cortex of the brain and raising the threshold for seizures in the central nervous system.
• Urinary retention, constipation, sedation, and blurred vision are not commonly associated with this medication.