A nursing student is studying the body's response to an allergen. Which of the follow immunoglobulins is released during an allergic response?



• IgE binds to allergens and triggers histamine release from basophils

• IgG provides the majority of antibody-based immunity against pathogens

• IgD acts as a receptor for B cells to produce antimicrobial factors

• IgA prevents pathogen colonization in the muscosa, gut, and respiratory tract

• IgM eliminates pathogens during the early stages of humoral immunity, before there is sufficient IgG

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