A patient is given an intramuscular injection of depot medroxyprogesterone acetate. The nurse instructs the patient about common side effects, including


• The most common side effects of medroxyprogesterone acetate (Depo-Provera) are weight gain, decreased bone density, increased spotting, or amenorrhea.

• Weight loss and increased bone density are not side effects of Depo-Provera.

• Dizziness has been reported but is rare, not a common side effect.  The nurse should teach the common side effects.

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