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A patient is prescribed a high dose of aspirin for osteoarthritis. The nurse should instruct the patient to contact the physician if which of the following symptoms develop?

Explanation

•At high doses, aspirin can become ototoxic, causing ringing in the ears (tinnitus).

•Constipation and diarrhea are not grounds for immediately contacting a physician.

•Cold extremities may signal a lack of perfusion. This is a serious issue, but is unrelated to aspirin.

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