A patient is prescribed tamoxifen 20 mg P.O. twice a day for newly diagnosed metastatic breast cancer. While providing education to the patient, the nurse should include which possible side effect?
•Tamoxifen is an antineoplastic agent that competes with estrogen for binding sites. Hot flashes occur in over 60% of patients on tamoxifen.
•Other side effects may include vaginal bleeding, amenorrhea, menstrual changes, nausea, vomiting, rash, pruritus, osteoporosis, bone pain, and fractures.