A patient is taking colchicine for the treatment of gout. Due to colchicine's effects on the intestinal mucosa, the patient should be instructed to increase his intake of which vitamin?


• Colchicine alters the function of the ileal mucosa and interferes with intrinsic factor, causing malabsorption of vitamin B12.

• The patient may need to take vitamin B12 supplements in the form of a sublingual tablet in order to bypass the intestinal tract.

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