A patient recently diagnosed with hypothyroidism is prescribed Levothyroxine. The nurse should include which of the following in her teaching plan?

Do not take with antacids
Take early in the morning on an empty stomach

Explanation

•Levothyroxine should be taken early in the morning to avoid interfering with sleep as common side effects include insomnia, anxiety, and nervousness.

•Levothyroxine should not be taken with food due to the resulting decrease in absorption. Taking it first thing in the morning on an empty stomach provides the best rates of absorption. Levothyroxine is chelated with certain elements (ferrous, calcium, magnesium, etc.) so it should not be taken within 4 hours of multivitamins, antacids, or iron supplements.

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