A patient with newly diagnosed benign prostatic hypertrophy (BPH) is prescribed prazosin. To avoid dizziness and syncope, the nurse should instruct the patient to take medication

at bedtime

Explanation

• Prazosin is an alpha-blocker that often causes severe hypotension after the first dose. Dizziness and orthostatic hypotension are common side effects, even after the first dose. Patients should be advised to take the medication before bedtime to avoid syncope, dizziness, or lightheadedness. 

• Incorrect: Lying down is incorrect because prazosin has a duration of 6-12 hours, so taking the medication while lying down would not be effective at preventing side effects. Also, taking medications while lying down increases the risk for aspiration. 

• Incorrect: Taking with a full meal does not decrease side effects. 

• Incorrect: Taking prazosin in the hospital is not necessary and would not decrease the risk of side effects.  

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