The nurse is caring for a 16-year-old female diagnosed with von Willebrand disease. Which of the following clinical findings will support this diagnosis?


•In Von Willebrand’s disease, the body has a deficiency of von Willebrand factor (vWF). vWF helps release factor VIII and in its absence, factor VIII degrades, causing a prolonged aPTT and decreased platelet adhesion.

•Von Willebrand disease is the most common hereditary coagulation abnormality but it can also be aquired.

•A prolonged PT and increased INR occurs with a vitamin K deficiency or coumadin therapy.

•Increased platelet count may occur due to a malignancy or inflammation.

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