The nurse is caring for a patient diagnosed with von Willebrand disease. Which of the following clinical findings will support this diagnosis?
Explanation
•In Von Willebrand’s disease, the body has a deficiency of von Willebrand factor (vWF). vWF helps release factor VIII and, in its absence, factor VIII degrades causing a prolonged aPTT and decreased platelet adhesion. The patient has platelets, but they will not adhere together to form clots.
•Von Willebrand disease is the most common hereditary coagulation abnormality, but it can also be acquired.
Incorrect options:
•A prolonged PT and increased INR occurs with a vitamin K deficiency or Coumadin therapy.
•Increased platelet count may occur due to a malignancy or inflammation.
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