• Clinical manifestations of nephrotic syndrome include edema, proteinuria, and weight gain due to fluid overload.
•Minimal change disease is idiopathic in origin and causes nephrotic syndrome. Nephrotic syndrome is a nonspecific disorder in which the kidneys are damage and allow the leakage of proteins into the blood.
•Gross hematuria is associated with nephritic syndrome.
•Fever would occur only if there is infection.
•Hypertension may occur, but patients are generally normotensive.