The nurse is implementing a dexamethasone suppression test on a patient with Cushing's syndrome. Which of the following steps should the nurse plan on implementing?

Administer the dexamethasone at night and measure serum cortisol the following morning.


• Dexamethasone is administered at around 23:00 and then serum levels are measured the following morning.

• The dexamethasone suppression test measures the negative feedback mechanism between cortisol and adrenocorticotropic hormone (ACTH). Normally, an increase in cortisol will cause a decrease in ACTH secretion.

• This test helps differentiate among the different types of Cushing's syndrome.

Visit our website for other NCLEX topics now!