The nurse reviews lab results for a patient taking ticlopidine, an antiplatelet drug. Which laboratory value would indicate an adverse reaction to ticlopidine?

Neutrophils, 500 cells/mm3


• Ticlopidine (Ticlid) is known to cause pancytopenia, which is a reduction of white blood cells (including neutrophils), red blood cells, and platelets. 

• Neutropenia refers to a reduction in the blood neutrophil count to < 1000mm³ 

• Ticlopidine can also cause hyponatremia (low sodium), but is not known to cause hypokalemia (low potassium).

• The glucose level is high but is not associated with the use of ticlopidine. The hemoglobin level listed is within normal limits

Normal lab values are as follows:

Neutrophils: 2,500 - 8,000 cells/mm³ (55-70%)

Hemoglobin: 14 - 18 g/dl (male), 12 - 16 g/dl (female)

Glucose: 70 - 110 mg/dl (fasting),  ≥ 200  (casual)

Potassium: 3.5 - 5.0 mEq/L

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