Explanation
• Application sites for nitroglycerin transdermal patches must be rotated every application to prevent skin irritation and sensitization
• The preferred site for a nitroglycerin patch is the chest. It must be dry, clean, and hairless. Avoid placing the patch on irritated sites or areas with cuts
• Nitroglycerin patches must be applied for 12-14 hours followed by a 10-12 hour nitrate-free period to avoid developing tolerance