A confused patient is being admitted to the hospital and the nurse is attempting to gather his health history. The patient denies the presence of any diseases, but he admits to discontinuing donepezil. The nurse understands that this medication is used to treat


• Donepezil is a cholinesterase inhibitor used to treat Alzheimer's disease.

• Cholinesterase inhibitors work by inhibiting cholinesterase at the synaptic cleft, thereby increasing available acetylcholine. This delays the progression of Alzheimer's.

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