•Caution parents not to give aspirin to children with a fever because aspirin is associated with Reye’s syndrome.
•Reye’s syndrome is a potentially fatal disease that causes acute encephalopathy and fatty liver. The cause is unknown, but it is associated with children taking aspirin for a viral illness.
•An antipyretic should be given to children with a fever. Acetaminophen is an excellent antipyretic and it is the drug most often prescribed to reduce fever in children.
•Aspirin is not associated with adrenal dysfunction.