•A bone marrow biopsy is performed to confirm the diagnosis of leukemia through the examination of abnormal cells in the bone marrow.
•With ALL, bone marrow overproduces immature lymphocytes and soon becomes unable to continue normal production of other blood components. ALL is the most common type of leukemia in children.
•A lumbar puncture is performed to detect invasion into the CNS, but is not used to confirm the diagnosis.
•An abnormal CBC may suggest leukemia, but it is not used to confirm the diagnosis.
•A blood culture may be performed if infection is suspected.