A patient is prescribed micronized estradiol for the treatment of perimenopausal symptoms. The nurse should inform this patient that this medication increases the risk of:


•Estrogen therapy unopposed by progestin increases the risk for endometrial cancer. Estrogen therapy also increases the risk for heart disease, stroke, and thromboembolic events.

•Estrogen therapy has not been shown to increase the risk for liver cancer, lung cancer, or leukemia.

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